Has only A antigen on red cells (and B antibody in the plasma) There are 4 major blood groups determined by the presence or absence of two antigens (A and B) on the surface of red blood cells: Since some antigens can trigger a patient's immune system to attack the transfused blood, safe blood transfusions depend on careful blood typing and cross-matching. There are eight different common blood types, which are determined by the presence or absence of certain antigens, which are substances that can trigger an immune response if they are foreign to the human body.
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